Ben Thomas(Will Smith), geçmişindeki bazı hatalardan dolayı suçluluk duyan, intiharı düşünecek kadar depresif bir insandır. Kafasında devamlı intihar düşüncesinin dolaştığı Ben, hayatına giren tamamen yabancı 7 kişi vesilesiyle kefaretini ödeme şansını yakalayacak; bu sırada kalp hastalığı olan Emily'de (Rosario Dawson) aşkı bulacaktır.

Tim Thomas was a gifted aerospace engineer with a beautiful wife. Then, while using his cell phone while driving, his car wandered across lanes and he became responsible for the deaths of 7 others, including his wife. Unable to forgive himself, Tim sets out to give "pounds of flesh" that will give new life to 7 deserving individuals to make up for the 7 lives he destroyed. Tim intends to kill himself and to bestow gifts to 7 worthy people, which includes body organs and material possessions. He personally investigates 7 people to verify that they are indeed the right people he should help and plans to have his best friend see that his wishes are carried out after he is dead. When he begins to fall in love with one of the people he is trying to help, his plan threatens to unravel.