High-throughput lead optimization in drug discovery
by
Kshirsagar, Tushar.
Title
:
High-throughput lead optimization in drug discovery
Author
:
Kshirsagar, Tushar.
ISBN
:
9781420006964
Publication Information
:
Boca Raton : CRC Press, c2008.
Physical Description
:
ix, 243 p. : ill.
Series
:
Critical reviews in combinatorial chemistry
Series Title
:
Critical reviews in combinatorial chemistry
Contents
:
Application of parallel synthesis to the optimization of inhibitors of the ZipA-FtsZ protein-protein interaction / Lee D. Jennings -- Case studies of parallel synthesis in hit identification, hit exploration, hit-to-lead, and lead optimization programs / Alexander Ernst and Daniel Obrecht -- A successful application of parallel synthesis to computer-assisted structural optimization of new leads targeting human immunodeficiency virus-1 reverse transcriptase : the case of acylthiocarbamates and thiocarbamates / Angelo Ranise, Andrea Spallarossa, and Sara Cesarini -- How high-throughput medicinal chemistry can expedite lead discovery, lead optimization, and beyond / Rongshi Li -- Rapid lead identification of inhibitors of adenine nucleotide translocase: a case study of applying combinatorial chemistry techniques in drug discovery / Yazhong Pei, Walter H. Moos, and Soumitra Ghosh -- Parallel synthesis of anticancer, antiinflammatory, and antiviral agents derived from L- and D-amino acids / Robert C. Reid and David P. Fairlie -- Application of solid-phase parallel synthesis in lead optimization studies / Bijoy Kundu -- High-throughput solid-phase synthesis of nucleoside-based libraries in the search for new antibiotics / Dianqing Sun and Richard E. Lee.
Subject Term
:
High throughput screening (Drug development)
Combinatorial chemistry.
Drug development.
Added Author
:
Kshirsagar, Tushar.
Electronic Access
:
Library | Material Type | Item Barcode | Shelf Number | [[missing key: search.ChildField.HOLDING]] | Status |
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Online Library | E-Book | 286619-1001 | ONLINE | | Elektronik Kütüphane |