1. Overview of physical characterization methodology / Harry G. Brittain -- 2. Ultraviolet/visible diffuse reflectance spectroscopy / Harry G. Brittain -- 3. Vibrational spectroscopy / David E. Bugay and Adrian C. Williams -- 4. Magnetic resonance spectrometry / David E. Bugay -- 5. Particle morphology : optical and electron microscopies / Ann W. Newman and Harry G. Brittain -- 6. Particle size distribution / Cynthia S. Randall -- 7. X-ray powder diffractometry / Raj Suryanarayanan -- 8. Thermal methods of analysis / James A. McCauley and Harry G. Brittain -- 9. Micromeritics / Ann W. Newman -- 10. Physical and mechanical property characterization of powders / Gregory E. Amidon -- 11. Solubility of pharmaceutical solids / David J. W. Grant and Harry G. Brittain -- 12. Sorption of water by solids / Mark J. Kontny and George Zografi.