Chapter. 1. Why move HPC applications to the Cloud? -- Part. I. Foundations -- Chapter. 2. What is Cloud Computing? -- Chapter. 3. What do HPC applications look like? -- Part. II. Running HPC Applications in Cloud -- Chapter. 4. Deploying and Configuring Infrastructure -- Chapter. 5. Executing Traditional HPC Application Code in Cloud with Containerized Job Schedulers -- Chapter. 6. Designing Cloud-friendly HPC Applications -- Chapter. 7. Exploiting Hardware Accelerators in Clouds -- Part III. Cost and Performance Optimizations -- Chapter. 8. Optimizing Infrastructure for MPI Applications -- Chapter. 9. Harnessing Low-Cost Virtual Machines on the Spot -- Chapter. 10. Ensuring Application Continuity with Fault Tolerance Techniques -- Chapter. 11. Avoiding Resource Wastage -- Part. IV. Application Study Cases -- Chapter. 12. Biological Sequence Comparison on Cloud-based GPU Environment -- Chapter. 13. Oil & Gas Reservoir Simulation in the Cloud -- Chapter. 14. Cost effective deep learning on the cloud -- Appendix A. Deploying an HPC cluster on AWS -- Appendix B. Configuring a cloud-deployed HPC cluster.