Endotoxin: Structure Source and Effects -- Pathophysiology of Endotoxic Shock -- Host Resistance to Endotoxic Shock -- Endotoxin and Organ Cross-talk -- Endotoxin Measurement in Septic Shock -- Clinical Management of Endotoxemia: Antibiotics -- Clinical Management of endotoxemia: volume support -- Clinical Management of Endotoxemia: Corticosteroids -- Clinical Management of Endotoxemia: Vasoactive and Cardiostimulant Drugs -- Clinical Management of Endotoxemia: Source Control -- Clinical Management of Endotoxemia: Treatment of DIC -- Clinical Management of Endotoxemia: Metabolic and Nutritional Support -- Strategies to Reduce Endotoxin Activities -- Extracorporeal Removal of Endotoxin.