Chapter 1_A scoping review of research on the unfolding human microbiome landscape in the metagenomics era -- Chapter 2_Elucidating the Role of Gut-Brain-Axis in Neuropsychiatric and Neurological Disorders -- Chapter 3_Role of Gut Microbiome Composition in Shaping Host Immune System Development and Health -- Chapter 4_Understanding the probiotics and mechanism of immunomodulation interactions with the gut-related immune system -- Chapter 5_Antimicrobial agents induced microbiome dysbiosis and its impact on immune system and metabolic health -- Chapter 6_Nutritional Modulation of Gut Microbiota Alleviates metabolic and neurological disorders -- Chapter 7_Hepatocellular carcinoma and human gut microbiome: Association with disease and scope for therapeutic intervention -- Chapter 8_Influence of intestinal Microbiomes on the COVID progression and its effects by the immunotherapeutic modulation -- Chapter 9_The Human Breast Milk Microbiome: Establishment and resilience of microbiota over mother-infant relationship -- Chapter 10_The dynamics of skin microbiome: Association of microbiota with skin disorders and therapeutic interventions -- Chapter 11_Advances in human urinary microbiome: Functional role beyond infections -- Chapter 12_Role of microbiomes in defining the metabolic and regulatory networks that distinguishes between good health and a continuum of disease states -- Chapter 13_The microbiome- antibiotic resistome: Significant strategies towards Microbiome-Targeted therapeutic interventions in medicine -- Chapter 14_New paradigms on Microbiome diagnostics design and engineering -- Chapter 15_Microbiome Therapeutics-Emerging Concepts and Challenges in translational microbiome research -- Chapter 16_Insights on the new generation technologies and capabilities of bioinformatic tools to understand microbiome research and microbial world.