Section 1: Introduction of Alzheimer's Disease -- Chapter 1: Alzheimer's disease and drug targets -- Chapter 2: Oxidative stress and metals in Alzheimer's disease -- Chapter 3: Neuroinflammation in Alzheimer's disease -- Section 2: Biomarkers and Diagnosis in Alzheimer's Disease -- Chapter 4: Biomarkers of Alzheimer's disease -- Chapter 5: Naturally inspired fluorescent organic molecules as diagnostic and theranostic tools in Alzheimer's disease -- Chapter 6: Nanostructure-based molecules as diagnostic and theranostic tools in AD -- Section 3: Drug derivatives: A strategy for new multifunctional drug development for Alzheimer's Disease -- Chapter 7: Approved cholinesterase inhibitors-based derivatives: Synthesis and their biological evaluation -- Chapter 8: Memantine-based derivatives: Synthesis and their biological evaluation -- Section 4: Natural molecules inspired novel derivatives for Alzheimer's Disease -- Chapter 9: Huperzine-based derivatives: Design, synthesis, and anti-Alzheimer activity -- Chapter 10: Polyphenol: Development of polyphenol-inspired derivatives targeting pathological factors of AD -- Chapter 11: Flavonoid-based derivatives for modulating various targets of Alzheimer's disease -- Chapter 12: Vitamin-based derivatives for the management of Alzheimer's disease -- Section 5: Metal dyshomeostasis: A hypothesis for developing drugs for the treatment of Alzheimer's disease -- Chapter 13: Metal chelators as a potential therapeutic agent for Alzheimer's disease -- Chapter 14: Ferroptosis modulators: A potential therapeutic target in Alzheimer's disease -- Section 6. Natural products/Synthetic molecules as epigenetic modulators in Alzheimer's disease -- Chapter 15. Sirtuin modulator: Design, synthesis, and biological evaluation -- Chapter 16. Histone deacetylase Inhibitors: Design, synthesis, and biological evaluation.