Chapter 1 High-Z Materials for X-ray and Gamma-ray Detection in Medical Imaging -- Chapter 2 Large Area Thin Film CdTe as the Next Generation X-ray Detector for Medical Imaging Applications -- Chapter 3 Investigation of Structural Defects in (Cd,Zn)Te Crystals Grown by the Traveling Heater Method -- Chapter 4 Solution Growth of CdZnTe Crystals for X-Ray Detector -- Chapter 5 3-Dimensional Mapping of Carrier Lifetime and Mobility -- Chapter 6 Investigation on the polarization effect and depolarization technique of CZT detector under high flux rate X/γ-ray irradiation -- Chapter 7 Research on the performance of CZT detector in alpha particle detection -- Chapter 8 CdZnTeSe: Recent advances for radiation detector applications -- Chapter 9 Investigation of charge transport properties and the role of point defects in CdZnTeSe room temperature radiation detectors -- Chapter 10 Charge sharingand cross-talk effects in high-Z and wide-bandgap compound semiconductor pixel detectors -- Chapter 11 Effect of electron irradiation on spectroscopic properties of Schottky-barrier CdTe semiconductor detectors -- Chapter 12. A Path to produce High-Performance CdZnTe crystals.