Chapter 1 Hepatitis E Virus -- Chapter 2 Characteristics and Functions of HEV Proteins -- Chapter 3 Epidemiology of Hepatitis E -- Chapter 4 Hepatitis E as a Zoonosis -- Chapter 5 Genetic Evolution of Hepatitis E Virus -- Chapter 6 Transmission of Hepatitis E Virus -- Chapter 7 Immunobiology and Host Response to HEV -- Chapter 8 Cell Culture for hepatitis E virus -- Chapter 9 Stem Cell and organoid culture for hepatitis E virus -- Chapter 10 Lifecycle of hepatitis E Virus -- Chapter 11 Morphogenesis of Hepatitis E Virus -- Chapter 12 Animal Models for Hepatitis E Virus -- Chapter 13 Clinical Manifestations of Hepatitis E -- Chapter 14 Laboratory Diagnosis of HEV Infection -- Chapter 15 Treatment of Hepatitis E -- Chapter 16 Prophylactic Hepatitis E Vaccine -- Chapter 17 Puzzles for hepatitis E virus.