Chapter 1. Strain design and optimization methods for sustainable production -- Chapter 2. Designer and minimal cells for production of biomolecules -- Chapter 3. Recent advances in downstream processing deployed in the treatment of pharmaceutical effluents -- Chapter 4. Microbial conversion of waste to biomolecules -- Chapter 5. Biosensor for detecting biomolecules -- Chapter 6. Artificial Intelligence Assisted Production of Biomolecules -- Chapter 7. Escherichia coli cell factory for synthesis of biomolecules -- Chapter 8. Bacillus subtilis cell factory -- Chapter 9. Pseudomonas putida cell factory -- Chapter 10. Cyanobacteria for marine based biomolecules -- Chapter 11. Yeast cell factory for biomolecules -- Chapter 12. Plant cell factory for biomolecules -- Chapter 13. Genetic manipulation of crop for enhanced food quality and nutrition towards sustainable production -- Chapter 14. Insect cell factory for production ofbiomolecules -- Chapter 15. Mammalian cell factor for biomolecules -- Chapter 16. Genome editing guided production of biomolecules -- Chapter 17. Cell free protein synthesis system for sustainable production of biofuels -- Chapter 18. Challenges and opportunities in biomanufacturing.