Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs)
by
 
Gautam, Saurabh. editor.

Title
Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs)

Author
Gautam, Saurabh. editor.

ISBN
9783031284892

Edition
1st ed. 2023.

Physical Description
XVI, 442 p. 84 illus., 62 illus. in color. online resource.

Contents
Chapter 1: Bioprocessing and analytical development for virus-based therapeutics -- Chapter 2: Viral Vector Upstream Processing and Clarification -- Chapter 3: Upstream processing of viral therapeutics: From host cell expansion to virus production -- Chapter 4: Leveraging virus biology and host genetic conflicts for cell line development and engineering for virus-based therapeutics -- Chapter 5: Overview of Current Downstream Processing for Modern Viral Vectors -- Chapter 6: Filtration Principles and Techniques for Bioprocessing of Viral Vector-Based Therapeutics -- Chapter 7: Chromatographic purification of viruses: State of the art and current trends -- Chapter 8: Purifying Viral Vectors - A Review of Chromatography Solutions -- Chapter 9: Particle analytics - Comparative approaches for analysis of viral vectors -- Chapter 10: Phase-Appropriate Potency Assay Development for AAV-based Gene Therapy Products -- Chapter 11: Quantification of virus infectivity - the key assay for the development ofviral therapeutics -- Chapter 12: Product-related impurities in therapeutic virus bioprocessing -- Chapter 13: Process Analytical Technologies (PAT) and Quality by Design (QbD) for bioprocessing of virus-based therapeutics -- Chapter 14: Methods and practical considerations in imaging viral therapeutics -- Chapter 15: Application of NMR Spectroscopy in Viral Assembly Characterization -- Chapter 16: Improved Production Strategies for Oncolytic Measles Viruses as a Therapeutic Cancer Treatment -- Chapter 17: Recent Advancements and Challenges in Recombinant Expression for Commercial Production of Virus Like Particles (VLPs) -- Chapter 18: Oncolytic viruses and viral gene therapy vectors: Principles of safety.

Subject Term
Virology.
 
Biomedical engineering.
 
Biotechnology.
 
Microbial genetics.
 
Analytical biochemistry.
 
Therapeutics.
 
Biomedical Engineering and Bioengineering.

Added Author
Gautam, Saurabh.
 
Chiramel, Abhilash I.
 
Pach, Roland.

Added Corporate Author
SpringerLink (Online service)

Electronic Access
https://doi.org/10.1007/978-3-031-28489-2


LibraryMaterial TypeItem BarcodeShelf Number[[missing key: search.ChildField.HOLDING]]Status
Online LibraryE-Book527866-1001ONLINEElektronik Kütüphane