Chapter 1. Introduction to Cartilage Tissue; Development, Structure and Functions -- Chapter 2. Cartilage defects and diseases: conventional therapies and its limitations -- Chapter 3. Strategies to Control Mesenchymal Stem Cell Differentiation for Regenerating Phenotypically Defined Articular Cartilage -- Chapter 4. Single Cell Analysis Approaches in Diagnostic and Therapeutic -- Chapter 5. The Importance of Mechanical Stimulation in Cartilage Formation: Applications of Bioreactors -- Chapter 6. Signaling Pathways Regulating Cartilage Formation -- Chapter 7. Role and Application of Biomolecules for Regeneration of Cartilage Tissue -- Chapter 8. Extracellular Matrix Miomimicry for Cartilage Tissue Formation -- Chapter 9. Cartilage Tissue Engineering; Advances and Frontiers -- Chapter 10. Advances in Hydrogels for Cartilage Regeneration -- Chapter 11. Shape Memory Polymers in Cartilage Tissue Engineering -- Chapter 12. Widely-used Biomaterials in Cartilage Biofabrication -- Chapter 13. Importance of 3D Printing Techniques in Cartilage Tissue Engineering -- Chapter 14. Cell Therapy as a Novel Therapeutic Approach for Cartilage Diseases -- Chapter 15. Extracellular Vesicles: A Potent Therapeutic Tool for Cartilage Regeneration -- Chapter 16. Osteochondral unit Approach for Articular Cartilage Regeneration -- Chapter 17. Stem Cells Therapy for Cartilage Regeneration in Clinic; Challenges and Opportunities -- Chapter 18. Validation of Tissue-Engineered Constructs: Preclinical and Clinical Studies.