Chapter 1: Microbiome in the framework of Predictive, Preventive and Personalised Medicine -- Chapter 2: Artificial Intelligence-based Predictive, Preventive, and Personalised Medicine applied to Bacteraemia Diagnosis -- Chapter 3: Vaginal microbiome and its role in HPV induced cervical carcinogenesis -- Chapter 4: Microbiome in lean Individuals: Phenotype-specific Risks and Outcomes -- Chapter 5: Microbiome and Obesity -- Chapter 6: Pathophysiology-based approach for individualized use of probiotics and prebiotics for metabolic syndrome: implementing predictive, preventive, and personalized medical approach -- Chapter 7: Selection of prebiotic substances for individual prescription -- Chapter 8: Probiotic Administration for the Prevention and Treatment of Gastrointestinal, Metabolic and Neurological Disorders -- Chapter 9: Microbial therapy with indigenous bacteria. From idea to clinical evidence -- Chapter 10: Fecal microbiota transplantation in diseases not associated with Clostridium difficile: current status and future therapeutic option -- Chapter 11: Personalized microbiome correction by application of individual nutrition for type 2 diabetes treatment -- Chapter 12: Pro-, pre- and synbiotic supplementation and oxalate homeostasis in 3PM context: focus on microbiota oxalate-degrading activity -- Chapter 13: In vitro study of specific properties of probiotic strains for effective and personalized probiotic therapy -- Chapter 14: Probiotic concepts of predictive, preventive, and personalized medical approach for obesity: Lactic acid bacteria and Bifidobacteria probiotic strains improve glycemic and inflammation profiles -- Chapter 15: Oral Microbiome and Innate Immunity in Health and Disease: Building a Predictive, Preventive and Personalized Therapeutic approach.