Nuclear Receptors: From Structure to the Clinic
by
 
McEwan, Iain J. editor.

Title
Nuclear Receptors: From Structure to the Clinic

Author
McEwan, Iain J. editor.

ISBN
9783319187297

Edition
1st ed. 2015.

Physical Description
XI, 236 p. 43 illus., 33 illus. in color. online resource.

Contents
1. Twenty-five Years of Nuclear Receptor Structure Analysis: From the Laboratory to the Clinic -- Part A. ALLOSTERIC REGULATION AND NUCLEAR RECEPTOR COMPLEX DYNAMICS. -2. Corticosteroid Receptors -- 3. Glucocorticoid Receptor Structure and Function -- 4. What Determines the Difference in DNA Binding Between the Androgen and the Glucocorticoid Receptors? -- 5. Allosteric Regulation and Intrinsic Disorder in Nuclear Hormone Receptors -- 6. Structural Analyses of Ordered and Disordered Regions in Ecdysteroid Receptor -- 7. Structural Analysis of Heterodimeric Nuclear Receptors -- Part B. NUCLEAR RECEPTOR CO-REGULATORY PROTEIN INTERACTIONS -- 8. Primate-specific Multi-functional Androgen Receptor Coregulator and Proto-oncogene Melanoma Antigen-A11 (MAGE-A11) -- 9. Assembly and Regulation of Nuclear Receptor Corepressor Complexes -- Part C. TAKING NUCLEAR RECEPTOR STRUCTURE INTO THE CLINIC -- 10. Thinking Outside the Box: Alternative Binding Sites in the Ligand Binding Domain of Nuclear Receptors.-11. Selective Estrogen Receptor Modulators (SERMs) and Selective Androgen Receptor Modulators (SARMs).

Subject Term
Medical genetics.
 
Endocrinology.
 
Human physiology.

Added Author
McEwan, Iain J.
 
Kumar, Raj.

Added Corporate Author
SpringerLink (Online service)

Electronic Access
https://doi.org/10.1007/978-3-319-18729-7


LibraryMaterial TypeItem BarcodeShelf Number[[missing key: search.ChildField.HOLDING]]Status
Online LibraryE-Book530049-1001ONLINEElektronik Kütüphane