Kinesins and Cancer
by
 
Kozielski, FSB, Frank. editor.

Title
Kinesins and Cancer

Author
Kozielski, FSB, Frank. editor.

ISBN
9789401797320

Edition
1st ed. 2015.

Physical Description
X, 271 p. 50 illus., 32 illus. in color. online resource.

Contents
Preface -- The kinesin superfamily -- The discovery and development of Eg5 inhibitors for the clinic -- Mechanism of action of Eg5 inhibitors -- Clinical trials of mitotic kinesin inhibitors -- Kif15; a useful target for anti-cancer therapy?.- Down-regulating CENP-E activity: for better or for worse -- The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target.-Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy -- Chromokinesins in genome maintenance and cancer -- Kif14: a clinically relevant kinesin and potential target for cancer therapy -- Kinesin-8 members and their potential as biomarker or therapeutic target -- The kinesin-6 members MKLP1, MKLP2 and MPP -- Non-motor spindle proteins as cancer chemotherapy targets -- Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons -- Index.

Subject Term
Cancer.
 
Cytology.
 
Medicinal chemistry.
 
Proteins .
 
Oncology.
 
Cancer Biology.
 
Cell Biology.
 
Protein Biochemistry.

Added Author
Kozielski, FSB, Frank.

Added Corporate Author
SpringerLink (Online service)

Electronic Access
https://doi.org/10.1007/978-94-017-9732-0


LibraryMaterial TypeItem BarcodeShelf Number[[missing key: search.ChildField.HOLDING]]Status
Online LibraryE-Book530089-1001ONLINEElektronik Kütüphane