1. Introduction / Ferenc A. Jolesz and Kullervo H. Hynynen -- 2. Fundamental principles of therapeutic ultrasound / Kullervo H. Hynynen -- 3. Fundamental principles of magnetic resonance temperature imaging / R. Jason Stafford and John D. Hazle -- 4. Experimental uses of magnetic resonance imaging-guided focused ultrasound surgery / Nathan McDannold -- 5. Integrated therapy delivery systems / Kullervo H. Hynynen and Nathan McDannold -- 6. Treatment planning / Gregory T. Clement -- 7. Current and future clinical applications of magnetic resonance imaging-guided focused ultrasound surgery / Ferenc A. Jolesz and Clare M.C. Tempany -- 8. Magnetic resonance imaging-guided breast focused ultrasound surgery / Eva C. Gombos and Daniel F. Kacher -- 9. Uterine fibroids and MRI-guided focused ultrasound surgery / Miriam M.F. Hanstede, Elizabeth A. Stewart, and Clare M.C. Tempany -- 10. MRI-guided focused ultrasound treatment of the brain / Kullervo H. Hynynen and Ferenc A. Jolesz -- 11. New clinical applications of magnetic resonance-guided focused ultrasound / Wladyslaw M.W. Gedroyc -- 12. Targeted drug delivery / Manabu Kinoshita -- 13. Blood-brain-barrier opening / Nathan McDannold and Kullervo H. Hynynen -- 14. Ultrasound-induced expression of a heat shock promoter-driven transgene delivered in the kidney by genetically modified mesenchymal stem cells : a feasibility study / Beatrice Letavernier. [et al.] -- 15. Ultrasound-induced apoptosis / Natalia Vykhodtseva and Manabu Kinoshita.