1. Classification and evolution of increased cardiometabolic risk states / William T. Cefalu -- 2. Insulin resistance and cardiometablic risk / William T. Cefalu -- 3. Role of obesity and body fat distribution in cardiometabolic risk / William T. Cefalu -- 4. Physiologic systems regulating energy balance, including the EC system / William T. Cefalu -- 5. Traditional metabolic risk factors / Kausik K. Ray, Christopher P. Cannon -- 6. Non-traditional risk factors of cardiometabolic risk / Kausik K. Ray, Christopher P. Cannon -- 7. Clinical outcomes of patients with cardiometabolic risk factors / Gregory Piazza, Christopher P. Cannon -- 8 Managing cardiometabolic risk : a brief review / Benjamin A. Steinberg, Christopher P. Cannon.