chapter 1 The assembly of very low density lipoproteins in the liver / chapter 2 Cardiovascular implications of partial, tissue-specific silencing of MTP / chapter 3 Acyl CoA: Diacylglycerol acyltransferases (DGATs) as therapeutic targets for cardiovascular disease / chapter 4 The biochemical and physiological roles of ACAT1 and ACAT2 in cholesterol homeostasis and atherosclerosis / chapter 5 Overview of intestinal lipid metabolism / chapter 6 The role of non-cholesterol sterols in the pathogenesis of atherosclerosis and their modulation by the sitosterolaemia locus / chapter 7 FXR: the molecular link between bile acid and lipid metabolism / chapter 8 Overview of HDL and reverse cholesterol transport / chapter 9 LXR as a therapeutic target for atherosclerosis / chapter 10 Endothelial lipase and the regulation of HDL metabolism / chapter 11 Cholesteryl ester transfer protein (CETP) inhibition as a therapeutic strategy for raising HDL-cholesterol levels and reducing atherosclerosis / chapter 12 Overview of insulin resistance and the metabolic syndrome / chapter 13 Peroxisome proliferator activated receptors and energy metabolism / chapter 14 Adipocytes and their secretory products / chapter 15 Regulation of adipocyte triglyceride storage / chapter 16 Role of innate immunity in atherosclerosis: immune recognition, immune activation and the atherosclerotic process / chapter 17 Role of CD44 in atherogenesis and its potential role as a therapeutic target / chapter 18 Lipoxygenases: potential therapeutic target in atherosclerosis / chapter 19 Role of secretory phospholipase A2 isozymes (Lp-PLA2)