part Part I: Computational Approaches -- chapter 1 Web Resources for Protein Analysis -- chapter 2 Artificial Neural Networks for Therapeutic Protein Engineering -- chapter 3 Phylogenetics and Medicinal Protein Engineering -- chapter 4 Clustering and Classification Approaches to Identifying Protein Properties -- chapter 5 Analysis of Coordinated Substitutions in Proteins -- part Part II: Protein Engineering Targets: Vaccine -- chapter 6 Tuning the Immune Response to Our Advantage: Design of Vaccines with Tailored Functions -- chapter 7 Modification of HIV-1 Envelope Glycoprotein to Enhance Immunogenicity -- chapter 8 Engineering Better Influenza Vaccines: Traditional and New Approaches -- chapter 9 Construction of Novel Vaccines on the Basis of Virus-Like Particles: Hepatitis B Virus Proteins as Vaccine Carriers -- chapter 10 Polyomavirus-Derived Virus-Like Particles -- chapter 11 Papillomavirus-Derived Virus-Like Particles -- chapter 12 Recombinant Vaccines against Hepatitis Viruses -- part Part III: Protein Engineering Targets: Diagnostics and Therapy -- chapter 13 Designer Diagnostic Reagents and Allergens -- chapter 14 Peptide-Based Diagnostic Assays -- chapter 15 Recombinant Antibodies -- chapter 16 Protein Engineering for HIV Therapeutics -- chapter 17 Recombinant Enzymes with New and Improved Properties -- part Part IV: Special Expression Systems -- chapter 18 Production of Pharmaceutical Compounds in Plants -- chapter 19 Plant Virus Biotechnology Platforms for Expression of Medicinal Proteins -- chapter 20 Alphaviruses: Multiplicity of Vectors and Their Promising Application as Vaccines and Cancer Therapy Agents.