chapter 1 A Brief Discussion of Proteomics — Definition – Concepts – Illusions -- chapter 2 An Overview of the Chemical Modification of Proteins -- chapter 3 The Application of Site-Specific Chemical Modification to Proteomics: Chemical Proteomics -- chapter 4 Sample Preparation for Proteomic Studies -- chapter 5 Prefractionation -- chapter 6 An Overview of Analytical Technologies Used in Proteomic Research -- chapter 7 Clinical Proteomics -- chapter 8 Validation Issues in Proteomics and the Transition from Research to Diagnostic Development.