Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. This book presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. It emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry.