chapter 1 BASIC DEFINITIONS AND CONCEPTS -- chapter 2 DATA GRAPHICS -- chapter 3 INTRODUCTION TO PROBABILITY: THE BINOMIAL AND NORMAL PROBABILITY DISTRIBUTIONS -- chapter 4 CHOOSING SAMPLES -- chapter 5 STATISTICAL INFERENCE: ESTIMATION AND HYPOTHESIS TESTING -- chapter 6 SAMPLE SIZE AND POWER -- chapter 7 LINEAR REGRESSION AND CORRELATION -- chapter 8 ANALYSIS OF VARIANCE -- chapter 9 Factorial Designs** -- chapter 10 TRANSFORMATIONS AND OUTLIERS -- chapter EXPERIMENTAL DESIGN IN CLINICAL TRIALS -- chapter 12 QUALITY CONTROL -- chapter 13 VALIDATION -- chapter 15 NONPARAMETRIC METHODS -- chapter 16 OPTIMIZATION TECHNIQUES AND SCREENING DESIGNS** -- chapter GLOSSARY -- chapter Appendix I: Some Properties of the Variance -- chapter Appendix II: Comparison of Slopes and Testing of Linearity: Determination of Relative Potency -- chapter Appendix III: Multiple Regression -- chapter Appendix IV: Tables -- chapter Appendix V: Outlier Tests and Chemical Assays -- chapter Appendix VI: Should a Single Unexplained Failing Assay Be Reason to Reject a Batch? -- chapter Appendix VII WHEN IS IT APPROPRIATE TO AVERAGE AND ITS RELATIONSHIP TO THE BARR DECISION -- chapter Appendix VIII EXCEL WORKBOOKS AND SAS PROGRAMS -- chapter Appendix IX: An Alternative Solution to the Distribution of the Individual Bioequivalence Metric -- chapter ANSWERS TO EXERCISES.