Neural dynamics of neurological disease
by
 
Shaw, Christopher A. (Christopher Ariel), author.

Title
Neural dynamics of neurological disease

Author
Shaw, Christopher A. (Christopher Ariel), author.

ISBN
9781118634479
 
9781118634738
 
9781118634523

Physical Description
1 online resource

Contents
The dynamics of neurological disease : current views and key issues -- Clinical and economic features of age-related neurological diseases -- Spectrum of neurological disease, clusters, and ubiquity -- Complexity, cascading failures, and neurological diseases -- Genetic determinants of neurological disease -- Environmental determinants of neurological disease and gene-toxin interactions -- The mystery and lessons of ALS-PDC -- Neurological disease models and their discontents : validity, replicability, and the decline effect -- The progression and the time line of neurological disease -- Development, aging, and neurological disease -- CNS-immune system interactions and autoimmunity -- The impact of synergy of factors in neurological disease -- The current status of neurological disease treatments -- The future of translational research in neurological disease -- Defining the limits for neurological disease treatments -- The politics and economics of neurological disease.

Abstract
The emerging understanding of age-related neurological disorders suggests that notions of a single causal gene/toxin being responsible is likely incorrect. Neurological disorders probably arise due to a unique intersection of multiple genetic and toxic factors, combined with additional contributions of age, stage of development, immune system actions, and more. This perspective leads to the view that rather than reflecting only one pathway to end-state disease, each is a spectrum disorder, and every individual case is therefore unique. Neural Dynamics of Neurological Disease argues for a fundamental rethinking of what we think we know about neurological disorders, how they arise and progress, and, crucially, what might be done to "cure" them. It first introduces the concept of neural dynamics of neurological disease, then examines various diseases and gives examples of the interplay of elements such as neural systems, cell types, and biochemical pathways that can contribute to disease. The concluding chapters point the way to how the emerging notion of neurological disease as a dynamic process may lead to more successful treatment options. Providing a cross-disciplinary approach to understanding the origin and progression of neurological disease, Neural Dynamics of Neurological Disease is a timely and valuable resource for neuroscientists, researchers, and clinicians.

Local Note
John Wiley and Sons

Subject Term
Nervous system -- Diseases.
 
Central nervous system -- Diseases.
 
Central Nervous System Diseases
 
Disease Progression
 
Aging -- physiology
 
Nervous System Diseases
 
Système nerveux -- Maladies.
 
Système nerveux central -- Maladies.
 
HEALTH & FITNESS -- Diseases -- General.
 
MEDICAL -- Clinical Medicine.
 
MEDICAL -- Diseases.
 
MEDICAL -- Evidence-Based Medicine.
 
MEDICAL -- Internal Medicine.
 
Neuroscience.
 
MEDICAL.
 
Central nervous system -- Diseases
 
Nervous system -- Diseases

Genre
Electronic books.
 
Internet Resources.

Electronic Access
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118634523


LibraryMaterial TypeItem BarcodeShelf Number[[missing key: search.ChildField.HOLDING]]Status
Online LibraryE-Book593151-1001RC346Wiley E-Kitap Koleksiyonu