Front Matter -- Semiotic Foundations of the Cultural Sciences. Cassirer and Symbolic Forms / Jean Lassgue -- Leroi-Gourhan and the Birth of the Symbolic Function / Arild Utaker -- Simondon, Language and Technology / Vincent Bentems -- Hermeneutics of Science, Hermeneutical Sciences. On the Philosophy of Mathematics: Reflections on "Making Science", Based on Cavaills / Franck Neveu -- The Semiotic Articulation of Textual Meaning: Significance, Signification, Designation and Expression / Regis Missire -- Semiotics of Cultures and Theoretical Hybridities: For a Renewal of Thought / Astrid Guillaume -- Literature and Arts Sciences. Challenges of Non-logocentric Semiotics of Cultures: Explorations Based on Music and the Notion of Significativity / Lia Kurts-Woste -- The Roles of a Semiotics of the Arts: Working Hypotheses for Overcoming the Shortcomings of the Past / Pierluigi Basso-Fossali -- Conclusion: Making Sense Between Science and Ethics.