Genetic analysis of complex diseases
by
 
Scott, William K., 1970- editor.

Title
Genetic analysis of complex diseases

Author
Scott, William K., 1970- editor.

ISBN
9781119104070
 
9781119104087
 
9781119104100

Edition
Third edition.

Physical Description
1 online resource : illustrations (some color)

General Note
Preceded by Genetic analysis of complex diseases / [edited by] Jonathan L. Haines, Margaret Pericak-Vance. 2nd ed. c2006.

Contents
Designing A Study For Identifying Genes In Complex Traits / William K. Scott, Marylyn D. Ritchie, Jonathan L. Haines, and Margaret A. Pericak-Vance -- Basic Concepts In Genetics / Kayla Fourzali, Abigail Deppen, and Elizabeth Heise -- Defining Disease Phenotypes / C. Hung and O. Bodamer -- Determining The Genetic Component of A Disease / Allison Ashley Koch and Evadnie Rampersaud -- Study Design For Genetic Studies / Dana C Crawford and Logan Dumitrescu -- Responsible Conduct of Research In Genetic Studies / Susan Estabrooks Hahn, Adam Buchanan, and Susan H. Blanton -- Linkage Analysis / Susan Blanton -- Data Management / Stephen D. Turner and William S. Bush -- Linkage Disequilibrium and Association Analysis / Eden R. Martin and Ren-Hua Chung -- Genome-Wide Association Studies / Jacob McCauley, Yogasudha Veturi, Shefali Setia Verma, and Marylyn D. Ritchie -- Bioinformatics of Human Genetic Disease Studies / Dale J. Hedges -- Complex Genetic Interactions / Data Mining/ Dimensionality Reduction -- William S. Bush and Stephen D. Turner -- Sample Size, Power, and Data Simulation / SARAH A. PENDERGRASS, YI-JU LI, SUSAN SHAO, MARYLYN D. RITCHIE.

Abstract
"Genetic Analysis of Complex Diseases, Third Edition provides a comprehensive introduction to the various strategies, designs, and methods of analysis for the study of human complex genetic disease. It offers a broad-based understanding of the problems and solutions based on successful applications in the design and execution of gene mapping projects. Chapters present clear and easily referenced overviews of the broad range of considerations involved in genetic analysis of human complex genetic disease, including design, sampling, data collection, linkage and association studies, and social, legal, and ethical issues. These studies promise a greater understanding of the genetic basis of common disorders, improved ability to detect risk factors, and development of new treatment strategies. The new edition of Genetics Analysis of Complex Disease is a unique and much needed resource as more and more clinical researchers are increasingly adopting a genetic perspective to investigate disease etiology, diagnostics, and prognostics"-- Provided by publisher.

Local Note
John Wiley and Sons

Subject Term
Medical genetics.
 
Genetic disorders.
 
Genetic Diseases, Inborn -- genetics
 
Disease -- genetics
 
Chromosome Mapping -- methods
 
Genetic Predisposition to Disease
 
Research Design
 
Genetic Research
 
Genetics, Medical
 
Genetic Diseases, Inborn
 
Génétique médicale.
 
Maladies génétiques.
 
Genetic disorders
 
Medical genetics

Added Author
Scott, William K., 1970-
 
Ritchie, Marylyn DeRiggi,

Electronic Access
https://onlinelibrary.wiley.com/doi/book/10.1002/9781119104100


LibraryMaterial TypeItem BarcodeShelf Number[[missing key: search.ChildField.HOLDING]]Status
Online LibraryE-Book596646-1001RB155 .G46 2022Wiley E-Kitap Koleksiyonu