Front Matter -- Lignins and Lignification / John Ralph, Hoon Kim, Fachuang Lu, Rebecca A Smith, Steven D Karlen, Nuoendagula, Koichi Yoshioka, Alexis Eugene, Sarah Liu, Canan Sener, Daisuke Ando, Mingjie Chen, Yanding Li, Leta L Landucci, Sally A Ralph, Vitaliy I Timokhin, Wu Lan, Jorge Rencoret, José C Río -- Synthesis of Epigallocatechin Gallate, Nobiletin, and Their Derivatives for Chemical-Biological Studies / Tomohiro Asakawa, Makoto Inai, Toshiyuki Kan -- Procyanidins in the Onset and Progression of Colorectal Cancer / Wei Zhu, Gerardo G Mackenzie, Patricia I Oteiza -- The Potential of Low Molecular Weight (Poly)phenol Metabolites for Attenuating Neuroinflammation and Treatment of Neurodegenerative Diseases / Daniela Marques, Rafael Carecho, Diogo Carregosa, Cláudia Nunes Santos -- Deciphering Complex Natural Mixtures through Metabolome Mining of Mass Spectrometry Data / Justin JJ Hooft, Madeleine Ernst, Daniel Papenberg, Kyo Bin Kang, Iris F Kappers, Marnix H Medema, Pieter C Dorrestein, Simon Rogers -- Application of MS-Based Metabolomics to Investigate Biomarkers of Apple Consumption Resulting from Microbiota and Host Metabolism Interactions / Fulvio Mattivi, Maria M Ulaszewska -- Non-Extractable Polyphenols Should be Systematically Included in Polyphenol Analysis / Enrique Báez-García, Sonia G Sáyago-Ayerdi, Jara Pérez-Jiménez -- Template-Mediated Engineering of Functional Metal-Phenolic Complex Coatings / Steve Spoljaric, JJ Richardson, Yi Ju, Frank Caruso -- Highly Efficient Production of Dihydroflavonol 4-Reductases in Tobacco Cells and Refinement of the BuOH-HCl Enzymatic Assay / Lingping Zhu, Saku Mattila, Roosa Matomäki, Lorenzo Mollo, Sharmin Ahamed, Sara M Abdou, Hany Bashandy, Teemu H Teeri -- A Long and Winding Road / Cathie Martin, Jie Li, Nick W Albert -- Analysis of Proanthocyanidins in Food Ingredients by the 4-(Dimethylamino)cinnamaldehyde Reaction / Daniel Esquivel-Alvarado, Emilia Alfaro-Viquez, Andrew Birmingham, Abigail Kramschuster, Christian G Krueger, Jess D Reed -- Reactions of Ellagitannins Related to Their Metabolism in Higher Plants / Takashi Tanaka -- Index