This book is a continuation of a series of presentations given at the III International Conference "Ecosystems Without Borders: Opportunities and Challenges" held at the Kaliningrad State Technical University in September 2023. The book presents research reflecting the transformation of ecosystems in the context of innovative development, science, technology and business. It also considers spatial aspects of ecosystems and the peculiarities of the formation of the creative class in the context of ecosystems. Theoretical articles aimed not only at the realization of the ideas of sustainable development in the economy but also at the realization of the ideas of structural transformation of innovation processes. The book is useful to a wide range of readers: practicing economists, students, graduate students and researchers, as well as government officials and company managers. The authors are confident that this book will serve as an important source of information and knowledge that will contribute to scientific and innovative progress in the field of sustainable development of society.