This book constitutes the refereed proceedings of the 22nd International Conference on Advances in Mobile Computing and Multimedia Intelligence, MoMM 2024, held in Bratislava, Slovak Republic, during December 2-4, 2024. The 10 full papers and 8 short papers in this book were carefully reviewed and selected from 34 submissions. They were organized in topical sections as follows: wearable and sensor-based data for human performance and interaction; mobile user experience, motivation, and behavior; medical and cognitive health applications; image, video, and multimedia processing; software and system intelligence.