Epidemiology and natural history -- Screening for Bladder Cancer -- Pathology and Staging: Histopathology and Cytopathology -- Pathology and Staging: Genetics and Molecular Biology -- Imaging in Localized and Advanced Bladder Cancer -- New Imaging Techniques in Staging of Urothelial Carcinoma of the Bladder -- Socioeconomic issues and improved quality of care -- Quality of life measures -- Prognostication and risk assessment -- Clinical trials and emerging therapeutic strategies in bladder cancer -- Improved diagnostic techniques -- Clinical scenario: Microscopic hematuria and atypical cytology in a 68 year old man with normal upper tract imaging -- Localized surgical therapy and surveillance -- Clinical Scenario: Initial high grade Ta tumor -- Clinical Scenario: Recurrent Ta tumor -- Clinical Scenario: Rapidly growing, high volume, low grade Ta tumor -- Clinical Scenario: Low grade T1 tumor -- Intravesical therapy -- Clinical Scenario: Initial CIS -- Management of BCG Recurrent Bladder Cancer -- Clinical Scenario: Persistent CIS and HIGH Grade Ta Bladder Cancer after BCG -- Maurizio Brausi -- Clinical Scenario: Presentation and Management of Significant Side Effects from Bacillus Calmette-Guérin Bladder Instillation -- Guideline-based management of non-muscle invasive bladder cancer: comparison of the AUA, EAU, ICUD and NCCN guidelines -- Open Radical Cystectomy -- Robotic cystectomy -- Clinical Scenario: T2 bladder tumor -- Urinary Diversion: Open and robotic techniques -- Chemoradiotherapy -- Clinical Scenario: 53 year-old man with a solitary, 2 cm, high-grade T2 tumor and focal CIS in the bladder dome who wants bladder preservation -- Management of Bladder Cancer, role of chemotherapy and controversies surrounding its application -- Clinical Scenario: Large volume, non metastatic T2 bladder tumor -- The role of pelvic lymphadenectomy at the time of radical cystectomy for bladder cancer -- Clinical Scenario: Unexpected positive nodes at radical cystectomy -- Surveillance andmonitoring -- Clinical Scenario: The Role of Perioperative Chemotherapy -- Management of Bladder Cancer with Pelvic Nodal Metastases After Complete Response to Chemotherapy -- Guideline based management muscle-invasive bladder cancer: NCCN, ICUD and EAU.