Part 1: Respiratory Support in the Critically Ill -- Oxygenation Targets in the ICU: Conservative or Liberal? -- The Hypoxic Drive, Supplemental Oxygen, and Hypercapnia -- Non-invasive Respiratory Support in Acute Hypoxemic Respiratory Failure -- PEEP Titration by the Bedside: How Do we Set it Right? -- Do Vigorous Spontaneous Respiratory Efforts Lead to Patient Self-inflicted Lung Injury (P-SILI)? -- Prone Ventilation in Acute Respiratory Distress Syndrome -- Neuromuscular Blocking Agents in Severe Acute Respiratory Distress Syndrome: Benefit or Harm? -- Ventilator-Associated Pneumonia: Newer Definitions, Controversies, and Perspectives -- Lung-protective Ventilation and Hypercapnia: How Much is Permissible? -- Tracheostomy in the ICU: Early or Late? -- Diaphragmatic Dysfunction in Critical Illness -- Weaning and Liberation from Mechanical Ventilation: Is my Patient Ready? -- When to Decannulate a Tracheostomy? -- Thrombolytic Therapy in Acute Pulmonary Embolism -- Part 2: Shock and Circulatory Support -- Corticosteroids in Sepsis: The Enduring Debate -- Hyperlactatemia in Critical Illness: Time for Reappraisal? -- Permissive Hypotension in Severe Trauma -- Assessment of Volume Responsiveness in the Critically Ill -- The Strategy of "De-resuscitation" in the Critically Ill -- Where Do We Stand with Early Goal-Directed Therapy in Sepsis? -- Normal Saline Versus Balanced Crystalloids Revisited -- Liberal Fluid Resuscitation vs. Early Vasopressors in Septic Shock -- Epinephrine and Outcomes Following Cardiac Arrest -- Targeted Temperature Management in Out-of-Hospital Cardiac Arrest -- Part 3: Acute Kidney Injury and Renal Replacement Therapy -- Augmented Renal Clearance in the Critically Ill -- Renal Replacement Therapy in Acute Kidney Injury: Is Timing all-Important? -- Optimizing the Dose of Renal Replacement Therapy -- Renal Replacement Therapy in The Critically Ill: Continuous vs. Prolonged Intermittent Therapies -- Part 4: Neurocritical Care -- Does Intracranial Pressure Monitoring Help in Severe Traumatic Brain Injury? -- Therapeutic Hypothermia in Traumatic Brain Injury -- Decompressive Craniectomy in Traumatic Brain Injury -- Optimzation of Osmotherapy in Cerebral Edema -- How Much Sedation in Critically Ill Patients on Mechanical Ventilation? -- Delirium in the Intensive Care Unit: Are we Paying Enough Attention? -- Clearing the Cervical Spine in Trauma Patients -- Part 5: Metabolic Support in Critical Illness -- Glycemic Control in the Critically Ill -- Vitamin C in Sepsis: End of the Debate? -- Part 6: The Gut and Nutrition -- Early or Supplemental Parenteral Nutrition vs. Enteral Nutrition Alone in The Critically Ill -- Stress Ulcer Prophylaxis in the ICU -- Do Tradition-Borne Fasting Practices Apply to ICU Patients with a Protected Airway? -- Part 7: Infections and Antibiotic Therapy -- Multidrug-resistant Gram-Negative Bacteria in the ICU: Do we Have Answers? -- Empirical Antibiotic Therapy: De-escalation Demystified -- Is it the End of the Road for Inhaled Antibiotic Therapy in Ventilator-Associated Pneumonia? -- Duration of Antibiotic Therapy in the Critically Ill -- Selective Digestive Decontamination: Helpful or Harmful? -- Part 8: Organizational Challenges in the ICU -- Which Organizational Structure to Pursue? The Open vs. Closed ICU Debate -- Adverse Events in the ICU: Building and Sustaining an Organizational Culture of Patient Safety -- How Effective are Rapid Response Systems? -- Part 9: Coagulopathy and Transfusion -- Transfusion Thresholds in Non-Bleeding Critically Ill Patients -- Tranexamic Acid in the Bleeding Patient -- Dengue-Related Thrombocytopenia and Platelet Transfusion -- Part 10: Burns -- Thermal Injury Resuscitation.