Pathology of genetically engineered and other mutant mice

Title:

Author:

Sundberg, John P., editor.

ISBN:

9781119624608

9781119624592

9781119624585

Uniform Title:

Pathology of genetically engineered mice.

Edition:

Second edition.

Physical Description:

1 online resource (xi, 547 pages) : illustrations (chiefly color)

General Note:

Preceded by Pathology of genetically engineered mice / Jerrold M. Ward ... [et al.]. 1st ed. 2000.

Contents:

Introduction to mouse pathology / Jerrold M. Ward, Peter Vogel, John P. Sundberg -- The mouse online : open mouse biology and pathology data resources for biomedical research / Dale A. Begley, Paul N. Schofield, and John P. Sundberg -- Mouse genetic nomenclature; the underpinning of mouse genetics / John P. Sundberg, Dale Begley, Melissa Berry, Michelle N. Perry, David Shaw, and Paul N. Schofield -- Discovering and validating mouse models of human diseases : the Cinderella effect / John P. Sundberg, Jerrold M. Ward, Peter Vogel, and Paul N. Schofield -- Embryos, placentas, and neonates / Brad Bolon and Jerrold M. Ward -- Ciliopathies / Peter Vogel and Laura L. Janke -- Hematopoietic and lymphoid tissues / Harm HogenEsch and John P. Sundberg -- Hematolymphoid neoplasms / Jerold E. Rehg -- Immunodeficient and humanized mice / Sara F. Santagostino, Sébastien Monette, Alessandra Piersigilli, Virginia L. Godfrey, and Harm HogenEsch -- Skin, hair, and nails / John P. Sundberg, Lloyd E. King, Jr., Raoul V. Kuiper -- Mammary gland / Alexander D. Borowsky and Robert D. Cardiff -- Respiratory system / Jerry M. Ward and John P. Sundberg -- Gastrointestinal tract / Jerrold M. Ward, Piper M. Treuting, M. Kay Washington -- Cardiovascular system / Kathleen Gabrielson, Akash Behera, Polina Sysa-Shah, Tyler J. Creamer, and Timothy Cooper -- Liver and pancreas / Maria L.Z. Dagli, Lucas M. Chaible, and Katja Steiger -- Neuromuscular system / Peter Vogel, Laura L. Janke, and Heather S. Tillman -- Endocrine system / Krista Marie DuBray La Perle -- Kidney and urinary bladder / Jeffrey B. Kopp, Cory F. Brayton, Jeffrey Everett, Avi Z. Rosenberg, Jerrold M. Ward -- Female reproductive tract / Darlene Dixon and Alexander Nikitin -- Male reproductive tract / Sue E. Knoblaugh, Hibret A. Adissu, Colin McKerlie, Robert D. Cardiff / Nervous system / Jessica M. Snyder, Katherine N. Gibson-Corley, and Enrico Radaelli -- Eye and ear / Heather Tillman, Laura Janke, Jerold Rehg, Peter Vogel -- Bones and teeth / Peter Vogel, John P. Sundberg, Cheryl Ackert-Bicknell.

Abstract:

"The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice"-- Provided by publisher.

Local Note:

John Wiley and Sons

Subject Term:

Transgenic mice -- Diseases.

Veterinary pathology.

Diseases -- Animal models.

Mice, Transgenic -- abnormalities

Disease Models, Animal

Pathology, Veterinary

Maladies -- Modèles animaux.

Souris transgéniques -- Maladies.

Pathologie vétérinaire.