Part I. Basics of Regenerative Medicine -- Chapter 1. Introduction to Regenerative Medicine -- Chapter 2. Prolotherapy -- Chapter 3. Blood Products -- Chapter 4. Bone Marrow Aspirate and the Use of Autologous Cells and Cellular Products in Regenerative Medicine -- Chapter 5. Adipose-Derived Stromal Stem Cells -- Chapter 6. Intra-annular Fibrin Discseel®Procedure to Diagnose and Treat Disc Pathology.-Chapter 7. Allograft Therapies in Regenerative Medicine -- Chapter 8. Adult Mesenchymal Stem Cell Collection and Banking -- Chapter 9. Exosomes -- Chapter 10. Exosomes in Stroke and Trauma: Current Concepts for Clinicians.-Part II. Imaging, Guidance, and Planning -- Chapter 11. Basics of Ultrasound -- Chapter 12. Ultrasound Guided Interventions: In-Plane and Out-of-Plane -- Chapter 13. Probe Selection -- Chapter 14. Diagnostic Musculoskeletal Ultrasound: Recognizing Pathology -- Chapter 15. Fluoroscopic Safety -- Chapter 16. Pre-procedural Imaging -- Chapter 17. Discography -- Chapter 18. Procedure Planningfor Ultrasound Guided Injections -- Chapter 19. Effects of Local Anesthetics and Contrast Agents on Regenerative Medicine Procedures -- Chapter 20. Medicolegal Aspects of Regenerative Medicine.-Chapter 21. Anti-Platelet and Anticoagulation Medications -- Chapter 22. Patient Factors Affecting Regenerative Medicine Outcomes.-Part III. Treatment Paradigms - Orthobiologics and Additional Utilities -- Chapter 23. Tendinopathy -- Chapter 24. Bone Marrow Derived Stem Cells and their Application in Pain Medicine -- Chapter 25. The Use of Platelet-Rich Plasma and Mesenchymal Stem Cells in the Lumbar and Lumbosacral Spine: Concepts, Literature Review and Recommendations -- Chapter 26. Adipose Derived Regenerative Cellular Therapy of Chronic Wounds -- Chapter 27. Aesthetic Surgery Applications for Adipose-Derived Stem Cells.