Preface -- Copy number variants and epilepsy: new emerging syndromes -- Mutations of ion channels in genetic epilepsies -- LGI1 dysfunction in inherited and acquired epileptic disorders -- Glioneuronal tumors and epilepsy: clinico-diagnostic features and surgical strategies -- Metabolic causes of epilepsy -- New insights into mechanisms underlying generalized reflex seizures -- Current status and future prospective of neuroimaging for epilepsy -- The complex relationship between epilepsy and headache and the concept of ictal epileptic headache -- Epilepsy and immune system: a tour around the current literature -- Novel molecular targets for drug-treatment of epilepsy -- Reproductive hormones in epilepsy therapy: from old promises to new hopes -- Neuromodulation for the treatment of drug-resistant epilepsy -- New radiosurgical paradigms to treat epilepsy using synchrotron radiation.