part Section 1: Vertebrate Visual Phototransduction -- chapter 1 Biophysical Approaches to the Study of G-Protein Structure and Function -- chapter 2 Photoactivation of Rhodopsin and Signal Transfer to Transducin -- chapter 3 How Rod Arrestin Achieved Perfection: Regulation of Its Availability and Binding Selectivity -- chapter 4 Function and Regulation of PDE6 -- chapter 5 Biochemical Characterization of Phototransduction RGS9-1–GAP Complex -- chapter 6 Guanylate Cyclase-Based Signaling in Photoreceptors and Retina -- chapter 7 Transgenic Strategies for Analysis of Photoreceptor Function -- part Section 2: Vertebrate Nonvisual Phototransduction -- chapter 8 Melanopsin Signaling and Nonvisual Ocular Photoreception -- part Section 3: Invertebrate Visual Phototransduction -- chapter 9 Phototransduction in Drosophila: Use of Microarrays in Cloning Genes Identified by Chemically Induced Mutations Causing ERG Defects -- part Section 4: Insulin Receptor-Based Signaling in the Vertebrate Retina -- chapter 10 Insulin Receptor-Based Signaling in the Retina -- chapter 11 Probing the Interactions between the Retinal Insulin Receptor and Its Downstream Effectors -- part Section 5: Signal Transducton in Vertebrate Retinal Development and Vascular Homeostasis -- chapter 12 Signal Transduction in Retinal Progenitor Cells -- chapter 13 Probing the Hedgehog Pathway in Retinal Development -- chapter 14 Thrombospondin-1 Signal Transduction and Retinal Vascular Homeostasis -- part Section 6: Lipid Mediators and Signaling in the RPE -- chapter 15 Lipidomic Approaches to Neuroprotection Signaling in the Retinal Pigment Epithelium.