chapter 1 Drosophila as a Genetic Model System for Understanding Human Biology and Disease -- chapter 2 Caenorhabditis elegans as a Model for Human Biology and Disease -- chapter 3 Transgenic Mouse Models -- chapter 4 Genetic Models of Respiratory Tract Development: From Invertebrates to Vertebrates -- chapter 5 Development of Branched Structures and the Cellular Response to Hypoxia: An Evolutionary Perspective -- chapter 6 Study of Anoxia Tolerance: Use of a Novel Genetic Approach and Animal Model -- chapter 7 Control of Oxygen Homeostasis by Hypoxia-Inducible Factor 1: Essential Roles in Embryogenesis, Physiology, and Disease Pathogenesis -- chapter 8 A Genetic Model for Cardiac Pattern Formation and Cell Fate Determination -- chapter 9 Cardiac Development in Vertebrates -- chapter 10 Genetic Defects Resulting in Abnormalities of Vertebrate Left–Right Asymmetry Provide Insight Into the Underlying Developmental Mechanisms -- chapter 11 Zebrafish: A Developmental and Genetic Model for Hematopoiesis and Hematopoietic Disorders -- chapter 12 Evolving Paradigms in Vasculogenesis and Angiogenesis -- chapter 13 Mouse Genetic Models in Atherosclerosis and Lipid Metabolism Research -- chapter 14 Apoptosis in Development and Disease -- chapter 15 Fly Clocks.