chapter PERSPECTIVES / chapter 1 OVERVIEW: TYROSINE KINASE SIGNALING IN INSULIN ACTION / chapter 2 DEFECTS IN EARLY INSULIN SIGNALING IN SKELETAL MUSCLE / chapter 3 DEFECTS IN INTERMEDIATE INSULIN SIGNALING IN SKELETAL MUSCLE: PHOSPHATIDYLINOSITOL (PI) 3-KINASE AND GLUCOSE TRANSPORT / chapter 4 Glucose Transport in Muscle / chapter 5 THE GLUT4 COMPARTMENTS OF SKELETAL MUSCLE / chapter 6 ADVERSE METABOLIC CONSEQUENCES OF HYPERGLYCEMIA (“GLUCOSE TOXICITY”): IMPLICATIONS FOR THE PATHOGENESIS OF DIABETES MELLITUS -- chapter 7 CELLULAR MEDIATORS OF GLUCOSE-INDUCED AUTOREGULATION OF HEXOSE TRANSPORT / chapter 8 PHYSIOLOGICAL ADAPTATIONS IN GLUCOSE UTILIZATION OF SKELETAL MUSCLE / chapter 9 FATTY ACIDS AND MUSCLE INSULIN RESISTANCE / chapter 10 Role of AMP Kinase and Malonyl CoA in Exercise-stimulatcd Skeletal Muscle Metabolism and Insulin Action / chapter 11 THE USE OF MOUSE TRANSGENIC AND HOMOLOGOUS RECOMBINATION TECHNOLOGIES TO ANALYZE THE PHYSIOLOGIC BASIS OF GLUCOSE HOMEOSTASIS / chapter 12 TRANSGENIC APPROACH TO INSULIN SIGNALING / chapter 13 TRANSGENIC MODELS TO STUDY GLUCOSE TRANSPORT AND METABOLISM IN SKELETAL MUSCLE / chapter Glucose utilization index -- chapter 14 INSULIN RESISTANCE IN SKELETAL MUSCLE: A ROLE FOR IMPAIRED INSULIN ACTIVATION OF GLYCOGEN SYNTHASE / chapter 15 MUSCLE GLUT4 TRAFFIC AND INSULIN-RESISTANT STATES / chapter 16 GLUCOSE TRANSPORT IN HEART: SPECIAL EMPHASIS ON INSULIN RESISTANCE AND NIDDM / chapter 17 CELLULAR REDOX STATE AND INSULIN SENSITIVITY: POTENTIAL ROLE OF LIPOIC ACID / chapter 18 EXERCISE TRAINING AND MUSCLE INSULIN RESISTANCE: CELLULAR ADAPTATIONS / chapter 19 EFFECTS OF PHYSICAL EXERCISE ON THE DECREASED INSULIN ACTION CAUSED BY AGING / chapter 20 EFFECTS OF AGING ON GLUCOSE HOMEOSTASIS: CELLULAR APPROACHES / chapter 21 INSULIN RESISTANCE: WHOLE BODY MECHANISMS IN HUMANS / chapter 22 Cellu]ar Mechanisms