1. Dry eye : the problem / Stephen C. Pflugfelder -- 2. The lacrimal functional unit / Roger W. Beuerman. [et al.] -- 3. The normal tear film and ocular surface / Michael E. Stern, Roger W. Beuerman, and Stephen C. Pflugfelder -- 4. Dysfunction of the lacrimal functional unit and its impact on tear film stability and composition / Stephen C. Pflugfelder, Michael E. Stern, and Roger W. Beuerman -- 5. The conjunctiva and tear film maintenance / Margarita Calonge and Michael E. Stern -- 6. Mechanisms of the ocular surface immune response / Pedram Hamrah. [et al.] -- 7. Impact of systemic immune disease on the lacrimal functional unit / Robert I. Fox and Michael E. Stern -- 8. Sex and sex steroid influences on dry eye syndrome / David A. Sullivan -- 9. Pathological effects of lacrimal keratoconjunctivitis on the ocular surface / Steven Yeh, Stephen C. Pflugfelder, and Michael E. Stern -- 10. Impact of allergy on the ocular surface / Virginia L. Calder and S. Lightman -- 11. Ocular surface epithelial stem cells : implications for ocular surface homeostasis / Leonard P. K. Ang. [et al.] -- 12. Meibomian gland disease / William D. Mathers -- 13. Diagnostic approaches to lacrimal keratoconjunctivitis / Cintia S. De Paiva and Stephen C. Pflugfelder -- 14. Therapy of lacrimal keratoconjunctivitis / Stephen C. Pflugfelder and Michael E. Stern -- 15. Surgical therapy for ocular surface disorders / Michael T. Yen -- 16. Therapy of ocular cicatricial pemphigoid / Thanh Hoang-Xuan -- 17. Surgical therapy for corneal epithelial stem cell deficiency / Mei-Chuan Yang. [et al.] -- 18. Immunosuppressive therapy for ocular surface disorders / Andrew J.W. Huang.