ch. 1. Toxic chemical risk as science and social discourse -- ch. 2. Environmental pathways of toxic chemicals -- ch. 3. Dose-effect : the foundation of toxicological science -- ch. 4. Human populations at risk -- ch. 5. The cornerstone of risk assessment : toxicity testing in animals -- ch. 6. The body's defenses against chemical toxicity -- ch. 7. Mechanisms of chemical disease -- ch. 8. Human health risk assessment -- ch. 9. Ecological risk assessment -- ch. 10. Managing chemical risk in North America and Europe.