
Title:
Molecular and Cellular Iron Transport.
Author:
Templeton, Douglas M., 1954-
ISBN:
9780824744175
9780367800536
Physical Description:
1 online resource (842 pages)
Contents:
Preface -- Contents -- Contributors -- Iron Chemistry -- Transferrins -- The Transferrin Receptor -- Molecular Aspects of Release of Iron from Transferrin -- Ferritins Structural and Functional Aspects -- The Divalent Metal-Ion Transporter (DCT1/DMT1/Nramp2) -- Basolateral Transport of Iron in Mammalian Intestine From Physiology to Molecules -- HFE -- Regulation of Iron Homeostasis by Iron Regulatory Proteins 1 and 2 -- Iron-Response Element (IRE) Structure and Combinatorial RNA Regulation -- Frataxin and Mitochondrial Iron -- Siderophore Chemistry -- Iron Chelator Chemistry -- Iron Acquisition in Plants -- Iron Uptake in Yeast -- Bacterial Iron Transport -- Uptake of Transferrin-Bound Iron by Mammalian Cells -- Transport of Non-Transferrin-Bound Iron by Hepatocytes -- Iron Acquisition by the Reticuloendothelial System -- Iron Transport in the Central Nervous System -- Iron Uptake by Neoplastic Cells -- Novel Methods for Assessing Transport of Iron Across Biological Membranes -- Regulation of Intestinal Iron Transport -- Regulation of Systemic Iron Transport and Storage -- Regulation of Liver Iron Metabolism -- Iron Utilization in Erythrocyte Formation and Hemoglobin Synthesis -- Animal Models of Iron Transport and Storage Disorders -- Hemochromatosis Diagnosis and Management Following the Discovery of the Gene -- Transfusional Iron Overload -- Aceruloplasminemia -- Hereditary Hyperferritinemia Cataract Syndrome -- Other Disorders of Increased Iron Absorption Iron Overload in Africans and African Americans -- Iron Chelation -- Index.
Abstract:
This text analyzes the molecular mechanisms, chemical behaviour and regulation of iron transport in biological systems and offers novel methods for the assessment of iron transport across biological membranes. It details the characteristics and consequences of iron deficiency and excess to prevent diseases affecting major organ structures and promote bodily iron homeostasis.
Electronic Access:
Taylor & Francis https://www.taylorfrancis.com/books/9780367800536OCLC metadata license agreement http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
Copies:
Available:*
Library | Material Type | Item Barcode | Shelf Number | Status | Item Holds |
|---|---|---|---|---|---|
Searching... | E-Book | 543543-1001 | QP535 .F4 M654 2002 EB | Searching... | Searching... |
