chapter 1 History and Development of the Salicylates / chapter 2 The Industrial History of Analgesics: the Evolution of Analgesics and Antipyretics -- chapter 3 Occurrence, Properties and Synthetic Developments of the Salicylates -- chapter 4 Pharmacokinetics and Metabolism of the Salicylates -- chapter 5 Metabolism and Pharmacokinetics of Ibuprofen / chapter 6 Pharmacokinetics and Metabolism of Paracetamol (Acetaminophen) -- chapter 7 Pharmacology and Biochemistry of Salicylates and Related Drugs -- chapter 8 Side Effects and Toxicology of the Salicylates / chapter 9 Reye's Syndrome and Aspirin / chapter 10 Salicylates in the Treatment of Acute Pain / chapter 11 Acetylsalicylic Acid for the Prevention and Treatment of Thromboembolic Diseases -- chapter 12 Use of Salicylates in Rheumatic and Related Conditions -- chapter 13 Aspirin and NSAIDs in the Prevention of Cancer, Alzheimer's Disease and other Novel Therapeutic Actions.