Pharmaceutical gene delivery systems

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Title:

Author:

Rolland, Alain, 1959- , editor.

ISBN:

9781135541262

Edition:

First edition.

Physical Description:

1 online resource (456 pages).

Series:

Drugs and the pharmaceutical sciences

Drugs and the pharmaceutical sciences.

Contents:

chapter 1 Introduction to Gene Therapy and Guidelines to Pharmaceutical Development / chapter 2 Sustaining Transgene Expression In Vivo / chapter 3 Expression Systems: Regulated Gene Expression / chapter 4 Mechanisms for Cationic Lipids in Gene Transfer / chapter 5 Polymer-Based Gene Delivery Systems / chapter 6 Chimeric Gene Delivery Systems / chapter 7 Adenoviral Vectors for Gene Delivery / chapter 8 Gene Delivery Technology: Adeno-Associated Virus / chapter 9 Retrovectors Go Forward / chapter 10 Device-Mediated Gene Delivery: A Review / chapter 11 Nonviral Approaches for Cancer Gene Therapy / chapter 12 Replicating Adenoviral Vectors for Cancer Therapy / chapter 13 Cardiovascular Gene Therapy / chapter 14 Pulmonary Gene Therapy / chapter 15 Artiﬁcial Chromosomes

Abstract:

This volume examines the advantages and limitations of the major gene delivery systems and offers guidelines to select the most appropriate viral or synthetic delivery system for specific therapeutic applications. It discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancerous, cardiovascular, pulmonary, genetic, and infectious diseases.

Subject Term:

Drug delivery systems.

Gene therapy.

Gene Transfer Techniques.

Genetic Therapy.

Genetic Vectors -- therapeutic use.

HEALTH & FITNESS -- Diseases -- Genetic.

MEDICAL -- Genetics.

MEDICAL / Genetics.

SCIENCE / Life Sciences / Genetics & Genomics.

Added Author:

Rolland, Alain, 1959- ,