Introduction and examples -- Study design and protocol development -- Models for longitudinal studies I -- Models for longitudinal studies II -- Moderation and mediation -- Characterization of missing data -- Analysis of studies with missing data -- Simple imputation -- Multiple imputation -- Pattern mixture and other mixture models -- Random effects dependent dropout -- Selection models -- Multiple endpoints -- Composite endpoints and summary measures -- Quality adjusted life-years (QALYs) and Q-TWiST -- Analysis plans and reporting results.