chapter 1 Impact of DNA Methylation on Health and Disease -- chapter 2 Uses of DNA Methylation in Cancer Diagnosis and Risk Assessment -- chapter 3 DNA Methylation in X Inactivation, Imprinting, and Associated Diseases -- chapter 4 Studying Mammalian DNA Methylation: Bisulfite Modification -- chapter 5 Bisulfite PCR-Based Techniques for the Study of DNA Methylation -- chapter 6 Microarray Analysis of DNA Methylation Targets Identified by Methyl-CpG-Binding Proteins -- chapter 7 Arbitrarily Primed-PCR and Related DNA Methylation Methodologies -- chapter 8 Discovering DNA Methylation Differences with Restriction Landmark Genomic Scanning -- chapter 9 Quantitative Determination of 5-Methylcytosine DNA Content: HPCE and HPLC -- chapter 10 Qualitative Determination of 5-Methylcytosine and Other Components of the DNA Methylation Machinery -- chapter 11 Mouse Models for the Study of DNA Methylation -- chapter 12 DNA Demethylating Agents: Concepts -- chapter 13 DNA Demethylating Agents: Preclinical Evaluation as Anticancer Agents -- chapter 14 DNA Demethylating Agents: Clinical Uses.