Title:
Mass spectrometry and stable isotopes in nutritional and pediatric research
Author:
Schierbeek, Henk, 1956- editor.
ISBN:
9781119341246
9781119341185
Physical Description:
1 online resource
Contents:
Wiley Series on Mass Spectrometry; Title Page; Copyright; Table of Contents; List of Contributors; Introduction; List of Abbreviations; Chapter 1: Mass Spectrometry Techniques for In Vivo Stable Isotope Approaches; 1.1 Introduction; 1.2 Nomenclature for Light-Stable Isotope Changes; 1.3 Mass Spectrometry Techniques; 1.4 Choice of Mass Spectrometric Techniques and Applications to Measure Isotopic Enrichments in Metabolic Studies; 1.5 Conclusion and Future Perspectives; References; Chapter 2: Stable Isotope Technology; 2.1 History; 2.2 Definition; 2.3 Safety.
2.4 Stable Isotopes and Natural Abundances2.5 Stable Isotope Selection; 2.6 Single or Multiple Label Selection; 2.7 Precursor Model; 2.8 Simultaneous Infusion; 2.9 Infusion Techniques; 2.10 Steady State; 2.11 Pool Selection; 2.12 Pool Models; 2.13 Flux: Synthesis and Breakdown; 2.14 Nitrogen Balance; 2.15 Doubly Labeled Water Method; 2.16 Whole-body Protein Synthesis; 2.17 Specific Protein Synthesis; 2.18 Calculations; 2.19 Considerations and Drawbacks of Isotopic Tracers; 2.20 Conclusion; References; Chapter 3: Stable Isotopes in Nutritional and Pediatric Research; 3.1 Introduction.
3.2 Ethical Aspects3.3 Applications of Stable Isotopes in Nutritional and Pediatric Research; 3.4 Conclusion; References; Chapter 4: Early-Life Nutrition and Stable Isotope Techniques; 4.1 Introduction; 4.2 Breast Milk versus Infant Formula; 4.3 Techniques to Monitor Milk Intake; 4.4 Body Composition in Term and Preterm Infants; 4.5 Amino Acid Requirement; 4.6 Clinical Applications; 4.7 Additional Applications; 4.8 Discussion; 4.9 Conclusion; 4.10 Future Perspectives; References; Chapter 5: Assessment of Amino Acid Requirement in Children Using Stable Isotopes; 5.1 Introduction.
5.2 Nutrient Needs and Definitions5.3 Methods to Determine Requirements; 5.4 Isotopic Tracer Methods; 5.5 Existing Methods to Determine Amino Acid Requirement for Neonates; 5.6 Use of the IAAO Method in the Pediatric Population; 5.7 Necessity for Performing the Study; 5.8 Biochemistry; 5.11 Analysis and Calculations; 5.12 Results; 5.13 Statistical Analysis; 5.14 Discussion; 5.15 Conclusion; 5.16 Future Perspectives; References; Chapter 6: Metabolism of Glutamine, Citrulline, and Arginine; Stable Isotopes Analyzing the Intestinal-Renal Axis; 6.1 Introduction; 6.2 Biochemistry.
6.3 Isotopic Model6.4 Study Design; 6.5 Mass Spectrometry Methods; 6.6 Clinical Applications; 6.7 Calculations; 6.8 Discussion and Future Perspectives; References; Chapter 7: Applications in Fat Absorption and Metabolism; 7.1 Introduction; 7.2 Biochemistry of Fat Absorption; 7.3 Isotope Model; 7.4 Study Design/Infusion Protocols; 7.5 Analytical Equipment; 7.6 Analytical Conditions; 7.7 Accuracy and Precision; 7.8 Calculations; 7.9 Clinical Applications; 7.10 Future Perspectives; References; Chapter 8: Materno-Fetal Lipid Kinetics; 8.1 Introduction.
Abstract:
A guide for scientists, pediatricians and students involved in metabolic studies in pediatric research Addresses the availability of modern analytical techniques and how to apply these techniques in metabolic studies Covers the whole range of available mass spectrometric techniques used for metabolic studies including Stable Isotope Methodology Presents the relevance of mass spectrometry and stable isotope methodology in pediatric research covering applications in Nutrition, Obesity, Metabolic Disorders, and Kidney Disorders Focuses on the interactions between nutrients and the endogenous metabolism within the body and how these factors affect the health of a growing infant.
Local Note:
John Wiley and Sons
Subject Term:
Genre:
Added Author:
Electronic Access:
https://onlinelibrary.wiley.com/doi/book/10.1002/9781119341185Copies:
Available:*
Library | Material Type | Item Barcode | Shelf Number | Status | Item Holds |
|---|---|---|---|---|---|
Searching... | E-Book | 593322-1001 | QP519.9 .M3 M3158 2017 EB | Searching... | Searching... |