N-Heterocyclic carbenes in organocatalysis

Title:

Author:

Biju, Akkattu T., editor.

ISBN:

9783527809042

9783527809059

Physical Description:

1 online resource

Contents:

Introduction to NHCs, synthesis, electronic and steric properties; The various modes of action of NHCs in organocatalysis; NHC-catalyzed umpolung of aldehydes: The benzoin reaction; Acyl anion addition to Michael acceptors: The Stetter reaction; NHC-catalyzed generation of homoenolates and related chemistry; NHC-catalyzed cascade processes for carbocycles and heterocycles synthesis; Oxidative NHC-catalysis; Acyl anion free NHC-organocatalysis; Dual-activation in NHC-catalysis; alpha, beta-unsaturated acylazolium generation using NHCs and addition of bisnucleophiles; Non-umpolung transformations in NHC-catalysis; NHC-catalyzed reactions involving saturated acylazoliums; NHC-catalyzed transformations of acid derivatives; Umpolung of Michael acceptors, alkyl halides and imines; Polymerization reactions catalyzed by NHCs; (Dynamic) Kinetic resolution and Desymmetrization reactions using NHC-catalysis; Application of NHCs in Natural products and biologically active compounds synthesis

Abstract:

Summarizing the emerging field of N-heterocyclic carbenes used in organocatalysis, this is an excellent overview of the synthesis and applications of NHCs focusing on carbon-carbon and carbon-heteroatom bond formation. Alongside comprehensive coverage of the synthesis, characteristics and applications, this handbook and ready reference also includes chapters on NHCs for polymerization reactions and natural product synthesis.

Local Note:

John Wiley and Sons

Subject Term:

Carbenes (Methylene compounds)

Heterocyclic chemistry.

Heterocyclic compounds.

Heterocyclic Compounds

Carbènes N-hétérocycliques.

Chimie des composés hétérocycliques.

Composés hétérocycliques.

Carbènes.

SCIENCE -- Chemistry -- Organic.