Cover image for Ribozymes
Title:
Ribozymes
ISBN:
9783527814527
Physical Description:
1 online resource
General Note:
Includes index.
Contents:
Nucleic Acid Catalysis: Principles, Strategies and Biological Function. The Chemical Principles of RNA Catalysis / Timothy J Wilson, David M J Lilley -- Biological Roles of Self-Cleaving Ribozymes / Christina E Weinberg -- Naturally Occurring Ribozymes. Chemical Mechanisms of the Nucleolytic Ribozymes / Timothy J Wilson, David M J Lilley -- The glmS Ribozyme and Its Multifunctional Coenzyme Glucosamine-6-phosphate / Juliane Soukup -- The Lariat Capping Ribozyme / Henrik Nielsen, Nicolai Krogh, Benoit Masquida, Steinar Daae Johansen -- Self-Splicing Group II Introns / Isabel Chilln, Marco Marcia -- The Spliceosome: an RNA-Protein Ribozyme Derived From Ancient Mobile Genetic Elements / Erin L Garside, Oliver A Kent, Andrew M MacMillan -- The Ribosome and Protein Synthesis / Paul Huter, Michael Graf, Daniel N Wilson -- The RNase P Ribozyme / Markus Gringer, Isabell Schencking, Roland Karl Hartmann -- Ribozyme Discovery in Bacteria / Adam Roth, Ronald Breaker -- Small Self-Cleaving Ribozymes in the Genomes of Vertebrates / Marcos Pena -- Engineered Ribozymes. Phosphoryl Transfer Ribozymes / Razvan Cojocaru, Peter J Unrau -- RNA Replication and the RNA Polymerase Ribozyme / Falk Wachowius, Philipp Holliger -- Maintenance of Genetic Information in the First Ribocell / m Kun -- Ribozyme-Catalyzed RNA Recombination / Benedict A Smail, Niles Lehman -- Engineering of Hairpin Ribozymes for RNA Processing Reactions / Robert Hieronymus, Jikang Zhu, Bettina Appel, Sabine Moller -- Engineering of the Neurospora Varkud Satellite Ribozyme for Cleavage of Nonnatural Stem-Loop Substrates / Pierre Dagenais, Julie Lacroix-Labont©♭, Nicolas Girard, Pascale Legault -- Chemical Modifications in Natural and Engineered Ribozymes / Stephanie Kath-Schorr -- Ribozymes for Regulation of Gene Expression / Julia Stifel, Jorg S Hartig -- Development of Flexizyme Aminoacylation Ribozymes and Their Applications / Takayuki Katoh, Yuki Goto, Toby Passioura, Hiroaki Suga -- In Vitro Selected (Deoxy)ribozymes that Catalyze Carbon-Carbon Bond Formation / Michael Famulok -- Nucleic Acid-Catalyzed RNA Ligation and Labeling / Mohammad Ghaem Maghami, Claudia H©œbartner -- DNAzymes. The Chemical Repertoire of DNA Enzymes / Marcel Hollenstein -- Light-Utilizing DNA zymes / Adam Barlev, Dipankar Sen -- Diverse Applications of DNAzymes in Computing and Nanotechnology / Matthew R Lakin, Darko Stefanovic, Milan N Stojanovic -- Ribozymes/DNAzymes in Diagnostics and Therapy. Optimization of Antiviral Ribozymes / Alfredo Berzal-Herranz, Cristina Romero-Lopez -- DNA zymes as Biosensors / Lingzi Ma, Juewen Liu -- Compartmentalization-Based Technologies for In Vitro Selection and Evolution of Ribozymes and Light-Up RNA Aptamers /Farah Bouhedda, Michael Ryckelynck -- Tools and Methods to Study Ribozymes. Elucidation of Ribozyme Mechanisms at the Example of the Pistol Ribozyme / Christoph Falschlunger, Josef Leiter, Ronald Micura -- Strategies for Crystallization of Natural Ribozymes / Benoit Masquida, Diana Sibrikova, Maria Costa -- NMR Spectroscopic Investigation of Ribozymes / Bozana Knezic, Oliver Binas, Albrecht Eduard Volklein, Harald Schwalbe -- Studying Ribozymes with Electron Paramagnetic Resonance Spectroscopy / Olav Schiemann -- Computational Modeling Methods for 3D Structure Prediction of Ribozymes / Pritha Ghosh, Chandran Nithin, Astha Joshi, Filip Stefaniak, Tomasz K Wirecki, Janusz M Bujnicki.
Abstract:
Timely and unique in its breadth of content, this all-encompassing and authoritative reference on ribozymes documents the great diversity of nucleic acid-based catalysis. It integrates the knowledge gained over the past 35 years in the field and features contributions from virtually every leading expert on the subject. Ribozymes is organized into six major parts. It starts by describing general principles and strategies of nucleic acid catalysis. It then introduces naturally occurring ribozymes and includes the search for new catalytic motifs or novel genomic locations of known motifs. Next, it covers the development and design of engineered ribozymes, before moving on to DNAzymes as a close relative of ribozymes. The next part examines the use of ribozymes for medicinal and environmental diagnostics, as well as for therapeutic tools. It finishes with a look at the tools and methods in ribozyme research, including the techniques and assays for structural and functional characterization of nucleic acid catalysts.
Local Note:
John Wiley and Sons
Holds:
Copies:

Available:*

Library
Material Type
Item Barcode
Shelf Number
Status
Item Holds
Searching...
E-Book 596955-1001 QP623.5 .C36
Searching...

On Order