Front Matter -- Conceptualizing Industrial Cyber-Physical Systems. General Concepts / Olivier Cardin, Damien Trentesaux -- Moving Towards a Sustainable Model: Societal, Economic and Environmental / Patrick Martin, Maroua Nouiri, Ali Siadat -- Sensing and Distributing Information Within Industrial Cyber-Physical Systems. Information Flow in Industrial Cyber-Physical Systems / Thierry Berger, Yves Sallez -- The Intelligent Product Concept / William Derigent -- Digitalizing at the Service of Industrial Cyber-Physical Systems. Virtualizing Resources, Products and the Information System / Theodor Borangiu, Silviu Raileanu, Octavian Morariu -- Cybersecurity of Industrial Cyber-Physical Systems / Antoine Gallais, Youcef Imine -- Controlling Industrial Cyber-Physical Systems. Industrial Agents: From the Holonic Paradigm to Industrial Cyber-Physical Systems / Paulo Leitão, Stamatis Karnouskos, Armando Walter Colombo -- Holonic Control Architectures / Olivier Cardin, William Derigent, Damien Trentesaux -- Learning and Interacting with Industrial Cyber-Physical Systems. Big Data Analytics and Machine Learning for Industrial Cyber-Physical Systems / Yasamin Eslami, Mario Lezoche, Philippe Thomas -- Human-Industrial Cyber-Physical System Integration: Design and Evaluation Methods / Marie-Pierre Pacaux-Lemoine, Frank Flemisch -- Transforming Industries with Industrial Cyber-Physical Systems. Impact of Industrial Cyber-Physical Systems on Reconfigurable Manufacturing Systems / Catherine da Cunha, Nathalie Klement -- Impact of Industrial Cyber-Physical Systems on Global and Interconnected Logistics / Shenle Pan, Mariam Lafkihi, Eric Ballot -- Impact of Industrial Cyber-Physical Systems on Transportation / John Mbuli, Damien Trentesaux -- Impacts of Industrial Cyber-Physical Systems on the Building Trades / William Derigent, Laurent Joblot -- Impact of Industrial Cyber-Physical Systems on the Health System / Franck Fontanil, Maria Di Mascolo -- Envisioning the Industrial Cyber-Physical Systems of the Future. Ethics and Responsibility of Industrial Cyber-Physical Systems / Sylvie Jonas, Françoise Lamnabhi-Lagarrigue -- Teaching and Learning ICPS: Lessons Learned and Best Practices / Bilal Ahmad, Freeha Azmat, Armando Walter Colombo, Gerrit Jan Veltink -- Conclusion -- List of Authors -- Index