This book overviews current advances in chitosan-based drug delivery systems, focusing on fabrication technology, methods, and applications. Chitosan, a renewable polysaccharide obtained by chitin deacetylation, is suitable as a biodegradable matrix for the production of different drug delivery systems owing to its biocompatibility, bio adhesive, antibacterial activity, haemostatic action, adsorption, properties, and functional capabilities. The current research trends are to continue innovative modifications of chitosan derivatives, nanotechnologies, stimuli-responsive delivery, and theragnostic techniques to improve promising chitosan-based drug delivery systems. This book is intended for scientists, researchers, and industrialists who are working on chitosan and chitosan-based drug delivery systems in the fields of pharmaceuticals, biomedical science, biomedical engineering, nanotechnology, and material engineering.