The book presents a comprehensive guide to eliminating ovarian hyperstimulation syndrome (OHSS) from assisted reproduction. This first-of-its-kind volume unites global experts from Israel, India, Turkey, and Italy to deliver a step-by-step clinical algorithm for safer, patient-centered IVF. The book explores OHSS from every angle-pathophysiology, prediction, prevention, and rescue, while introducing cutting-edge strategies such as metformin use, luteal phase modifications, freeze-all protocols, and in-vitro maturation (IVM). It evaluates the relevance of HCG triggers and presents emerging pharmacological solutions that reshape modern stimulation practices. Clinicians gain practical tools, visual aids, and evidence-based insights to minimize risk and maximize outcomes. The final chapter synthesizes two decades of research into a visionary protocol for OHSS-free IVF worldwide. With contributions from renowned figures like Eitan Lunenfeld, Raoul Orvieto, Shahar Kol, Kemal Ozgur, and Andrea Borini, this book serves as both a hands-on manual and an authoritative reference for ART professionals committed to advancing reproductive medicine without compromise.