This book describes the most recent strategies for the digitalization of railway sector that bring new challenges for the construction, operation, and maintenance of railway infrastructures. These strategies involve the development and application of new technologies and methodologies to enhance the sustainability and resilience of railway infrastructures particularly under extreme climate and operational events. In particular, the digital transformation involves the use of digital twins, augmented and virtual reality, forecast capabilities, risk and life-cycle analysis, cybersecurity, unmanned technologies for monitoring and inspection, computer vision, AI, risk and disaster management, among others. Presently, the literature is lacking a contribution that provides general and foundational knowledge across these and other topics. Therefore, this book provides valuable information for researchers, students, and professionals in railway engineering that want to developtheir knowledge and skills in this field.